Price of Obeticholic acid overseas

Obeticholic acid) is a synthetic derivative of the endogenous major bile acidObeticholic acid. Obeticholic acid was developed primarily for the treatment of liver and bile duct lesions. It has proven efficacy as an anticholestasis and antihepatotoxic drug. Currently, obeticholic acid has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of primary cholangitis (PBC). Obeticholic acid is still under investigation for primary sclerosing cholangitis and non-alcoholic steatohepatitis (NASH).

Obeticholic acid is mainly used to treat primary cholangitis, also called primary biliary cirrhosis, which is a chronic and progressive liver disease characterized by inflammation and destruction of intrahepatic bile ducts, resulting in the inability to discharge bile normally, ultimately leading to liver function damage. Obeticholic acid reduces liver inflammation and fibrosis, relieves symptoms and improves patients' quality of life by regulating the synthesis and excretion of bile acids. Obeticholic acid needs to be used under the supervision of a doctor and follow the doctor's medication instructions. Some side effects may occur during use, such as nausea, diarrhea, fatigue, etc.

The original drug of obeticholic acid has not yet been marketed in the country, so it has not been included in medical insurance. The original obeticholic acid drug marketed overseas is expensive, with each box costing around tens of thousands of yuan. The price is also affected by exchange rates and is unstable. It is understood that obeticholic acid has been produced as a generic drug and its ingredients are basically the same as those of the original drug. For example, the price of 5mg*30 tablets produced by a Bangladesh pharmaceutical factory is around RMB 1,000 per box (the price may fluctuate due to the exchange rate), and the price is cheap. For more drug information and specific prices, please consult a medical consultant.