What are the side effects of ibrutinib?

Ibrutinib is a targeted therapy drug commonly used to treat certain types of leukemia and lymphoma. Although ibrutinib reduces some of the side effects of traditional chemotherapy while providing effective treatment, it may still cause some side effects. The following are some common and important side effects associated with ibrutinib treatment:

Common side effects:

1.Bleeding tendency: Ibrutinib may cause bleeding tendency, such as nose bleeding, congestion and ecchymosis, gastrointestinal bleeding, etc. Patients should avoid blood-thinning medications and monitor closely for any unusual bleeding or bruising.

2.Hypertension: Some patients may develop high blood pressure while taking ibrutinib. Check your blood pressure regularly and follow your doctor's recommendations for treatment and monitoring.

3. Abnormal liver function: Ibrutinib may cause abnormal liver function, manifesting as jaundice, abdominal discomfort, fatigue and other symptoms. Patients should undergo regular liver function tests so that problems can be detected and treated early.

4.Fatigue: Fatigue is a common side effect during ibrutinib treatment. Patients should get enough rest and maintain a good lifestyle to reduce fatigue.

5.Digestive tract discomfort: Gastrointestinal discomfort including diarrhea, nausea, vomiting, etc. may occur when using ibrutinib. Your doctor can recommend medications to help control these symptoms.

6.Skin reactions: Ibrutinib may cause skin reactions such as itching, rash, dryness, and inflammation. Patients should avoid overexposure to the sun and use gentle skin care products.

Important side effects:

1.Heart problems: During ibrutinib treatment, some patients may experience heart problems, including arrhythmias, heart failure, etc. Doctors will perform regular electrocardiograms and heart monitoring to monitor heart health.

2.Hypertensive crisis: Although high blood pressure is a common side effect of ibrutinib, in some cases, it may trigger a hypertensive crisis that requires emergency treatment.

3.Infection: Ibrutinib may reduce the function of the immune system and increase the risk of infection. Patients should have regular blood tests to check their white blood cell count and avoid contact with sources of infection.

4.Development of new lumps: In some cases, new lumps or swollen lymph nodes may develop during treatment with ibrutinib. This may require further evaluation and processing.

5.Occurrence of other malignant tumors: There are reports that other malignant tumors may occur during ibrutinib treatment. Patients should receive regular cancer screenings.

6.Decreased bone density: Using ibrutinib may cause a decrease in bone density and increase the risk of fractures. Your doctor may recommend a bone density test and supplemental treatments.

It needs to be emphasized that different patients respond differently to the side effects of ibrutinib, and the severity of side effects also varies between individuals. Patients should communicate regularly with their doctor and follow their doctor's advice closely so that any discomfort or side effects can be recognized and dealt with promptly. Although ibrutinib may cause some discomfort, its potential to provide effective treatment that can improve patients' quality of life and prognosis is generally considered to be quite high.

Ibrutinib is currently on the market in China and is included in medical insurance. The domestic price ranges from 10,000 to 20,000. Due to different medical insurance policies in different places, the price is also different. For specific reimbursement information, please consult the local hospital pharmacy or medical insurance bureau. The cheaper types of ibrutinib abroad are generic drugs, mainly Indian generic drugs, Bangladeshi generic drugs and Laos generic drugs, with prices ranging from a few hundred to several thousand yuan. And the ingredients of generic ibrutinib drugs are basically the same as those of domestic ibrutinib drugs.