Indications of ozanimod hydrochloride capsules

Ozamod (ozanimod) contains ozanimod, a sphingosine 1-phosphate receptor modulator, as ozanimod hydrochloride (HCl), Ozamod is provided as an oral hard gelatin capsule containing 0.23, 0.46, or 0.92 mg of ozanimod, including the following two indications:

1. Multiple sclerosis (MS): Ozamod can treat relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Although these therapies are not curative, they have been shown to improve several indicators of disease activity, including relapse rates, new or enhancing MRI lesions, and disability progression. The American Academy of Neurology (AAN) recommends disease-modifying treatment for patients with relapsing MS who have recent relapses and/or MRI activity.

2. Ulcerative colitis (UC): Ozamod is indicated for the treatment of adults with moderately to severely active ulcerative colitis. Treatment goals include achieving and maintaining corticosteroid-free remission and promoting mucosal healing. Doctors choose specific treatments for UC based on the severity of the disease, the location/extent of the disease, the prognosis of the disease, and previously used therapies.

The original drug Ozamod has been launched in China, but it has been on the market for a short time and has not been included in the medical insurance. The specific price is not yet clear, and domestic purchase channels are relatively difficult. The price of Ozamod original drug specifications0.92*28 capsules per box listed overseas may be around 19,000 yuan (the price may fluctuate due to the exchange rate), which is expensive. There is currently no generic version of Ozamod produced and launched. For more drug information and specific prices, please consult the medical consultant of Yaode.