What are the side effects of ozanimod?

Ozamod (ozanimod) is used to treat relapsing multiple sclerosis (MS) in adults, including clinically isolated syndrome (CIS with onset of neurological symptoms lasting at least 24 hours), relapsing-remitting syndrome (symptoms that persist for at least 24 hours). It is also used to treat ulcerative colitis (a disease that causes swelling and ulcers in the lining of the colon [large intestine] and rectum) in adults. Ozamod is a drug called a sphingosine L-phosphate receptor modulator, which works by reducing the activity of immune cells that can cause nerve damage.

Adverse reactions reported in clinical trials of ozanimod in multiple sclerosis included upper respiratory tract infection, increased hepatic transaminases, orthostatic hypotension, urinary tract infection, back pain, and hypertension; in clinical trials of ozanimod in ulcerative colitis, adverse reactions included increased liver function tests, upper respiratory tract infection, and headache. Other adverse reactions include decreased heart rate, malignant tumors, allergic reactions (rash, urticaria), peripheral edema, etc. Ozamod overdose may cause adverse reactions such as drowsiness, fatigue, headache, dizziness, bradycardia, cardiac conduction defects, hypertension, liver damage, and nausea.

The original drug Ozamod has been launched in China, but it has been on the market for a short time and has not been included in the medical insurance. The specific price is not yet clear, and domestic purchase channels are relatively difficult. The price of Ozamod original drug specifications0.92*28 capsules per box listed overseas may be around 19,000 yuan (the price may fluctuate due to the exchange rate), which is expensive. There is currently no generic version of Ozamod produced and launched. For more drug information and specific prices, please consult the medical consultant of Yaode.