What are the side effects of Nilotinib?

The most common (greater than 10%) non-hematologic adverse drug reactions caused by nilotinib in adults with newly diagnosed Ph+CML-CP were rash, pruritus, headache, nausea, fatigue, alopecia, myalgia, and epigastric pain. The incidence of constipation, diarrhea, dry skin, muscle cramps, arthralgia, abdominal pain, peripheral edema, vomiting, and fatigue is low (less than or equal to 10% and greater than 5%), is mild to moderate in severity, is easily manageable, and usually does not require dose reduction.

In adult patients with drug resistance or intoleranceThe most commonly reported non-hematologic adverse drug reactions (greater than or equal to 10%) in adult patients with Ph+ CML-CP and CML-AP were rash, pruritus, nausea, fatigue, headache, constipation, diarrhea, vomiting, and myalgia. Common serious drug-related adverse reactions (greater than or equal to 1% and less than 10%) are thrombocytopenia, neutropenia, anemia, febrile neutropenia, pneumonia, leukopenia, intracranial hemorrhage, elevated lipase, and pyrexia. .

The original drug Nilotinib is marketed in China under the name Nilotinib and is covered by medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of 150mg*120 tablets per box may be around 9,000 yuan. The Indian version of Nilotinib is available overseas. The price of Nilotinib's original drug, 150mg*28 capsules per box, may be around RMB 1,000 (the price may fluctuate due to exchange rates). The ingredients of the original drug sold domestically and abroad are basically the same. Currently, there is no generic version of Nilotinib produced and launched. For more drug information and specific prices, please consult Yaode Medical Consultants.