How much does a box of Mobocertinib cost?

Mobocertinib is a drug used to treat non-small cell lung cancer (NSCLC), especially those carrying EG Patients with FRgene mutations, especially those who experience disease progression after EGFRtyrosine kinase inhibitor (TKI) treatment.

Mobotinib is currently on the market in China, but it is not included in medical insurance. Patients need to pay for it in full, so the price is very high. Please consult the local hospital pharmacy for specific prices. Other versions include the Hong Kong version of the original drug Mobotinib, which costs around 7,000 to 8,000 yuan. The generic drug of Mobotinib is mainly a Laotian generic drug. The price is about three to four thousand yuan, which is nearly half cheaper than the original drug. The ingredients of the original drug and the generic drug are the same.

Mobosetinib is mainly used to treat EGFR gene mutation-positive advanced or metastatic non-small cell lung cancer (NSCLC). It has unique efficacy in patients whose disease has progressed after treatment with EGFR TKIs, particularly those carrying the EGFR T790M mutation.

Mobosetinib belongs to the tyrosine kinase inhibitor (TKI) class of drugs. It prevents the growth and division of cancer cells by inhibiting the activity of EGFR (epidermal growth factor receptor). Unlike traditional EGFR TKI, mobosetinib also has a highly inhibitory effect on EGFR T790M mutation, which often leads to resistance to other EGFR TKI.

Mobosetinib is rapidly absorbed into the body, typically reaching peak concentrations within2 hours. It is mainly metabolized by the liver, in which CYP3A enzyme is the main pathway of its metabolism. Drug metabolites are mainly excreted in urine and feces.