How much does Vandetanib cost in 2023

Vandetanib (Vandetanib) is a once-daily, oral, tumor angiogenesis and tumor cell proliferation kinase inhibitor indicated for the treatment of patients with symptomatic or progressive medullary thyroid carcinoma (MTC) who have unresectable locally advanced or metastatic disease. Vandetanib is effective in treating medullary thyroid cancer in patients 5 years and older, however, it is uncertain how effective it will be in patients who do not have mutations (changes) in a gene called "rearrangement during transfection" (RET) or in patients whose RET mutation status is unknown.

Medullary thyroid cancer accounts for approximately 4% of all thyroid cancers, with a 10-year overall relative survival rate of 75%. Surgery is currently the standard treatment for patients with newly diagnosed localized MTC, and radioactive iodine therapy is not recommended for the treatment of MTC because MTC cells do not accumulate radioactive iodine. Vandetanib is the first tyrosine kinase inhibitor approved for this indication, demonstrated beneficial response rates and better PFS than placebo in a phase III randomized clinical trial, and is a well-tolerated oral agent. Side effects are common, can be problematic, and even fatal. The most common adverse events include diarrhea, nausea, fatigue, rash, acne, hypertension, headache, anorexia, and abdominal pain.

The original drug vandetanib has not yet been marketed in China, so it is not included in medical insurance. The original drug specifications of vandetanib listed overseasThe price of each box of 300mg*30 tablets may be more than 30,000 yuan (the price may fluctuate due to the exchange rate). There is currently no generic drug of vandetanib produced and launched. For more drug information and specific prices, please consult the medical consultant of Yaode.