How much does Trifluridine Tipiracil Tablets (Lonsurf) cost?

Lonsurf is a combination drug of the nucleoside metabolism inhibitor trifluridine and the thymidine phosphorylase inhibitor tipiracil. Treatment should be prescribed by a doctor experienced in the use of cancer drugs. This drug is only available with a prescription.

Trifluridine and tipiracil tablets are indicated for the treatment of adult patients with metastatic colorectal cancer, either alone or in combination with bevacizumab, who have previously received fluoropyrimidine, oxaliplatin, and irinotecan-based chemotherapy, anti- VEGF biologic therapy as well as anti-EGFR therapy for RAS wild-type; or metastatic gastric or gastroesophageal junction adenocarcinoma in patients who have received at least two prior chemotherapy regimens, including fluoropyrimidine, platinum, taxane, or irinotecan, and, if appropriate, HER2/NEU targeted therapy.

TrifluridineThe original drug of tipiracil tablets has been marketed in China under the trade name Langsif, but it has not yet entered the scope of medical insurance. The price of 15mg*20 tablets per box may be around 6,000 yuan. The price of the Hong Kong version of 15mg*20 tablets per box may be more than 10,000 yuan (the price may fluctuate due to exchange rates).

The Japanese version of trifluridine tipiracil tablets, original drug, specifications 20mg*20 tablets, may be priced around RMB 5,000 per box per box (the price may fluctuate due to exchange rates). There are also cheaper generic versions of trifluridine tipiracil tablets overseas, whose pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of a box of 15mg*20 tablets produced by an Indian pharmaceutical factory may be around RMB 1,000 (the price may fluctuate due to exchange rates).