Temozolomide medical insurance price

Temozolomide (Temozolomide) is a prodrug of the imidazotetrazine class. It requires non-enzymatic hydrolysis at physiological pH in vivo to alkylate adenine/guanine residues, causing DNA damage through an ineffective repair cycle and ultimately cell death. Temozolomide treatment is associated with myelosuppression, which may be more severe in women and elderly patients.

Before starting treatment, patientsANC must be ≥1.5 x 109/L and platelet count must be ≥100 x 109/L, and must be monitored weekly during the concomitant radiation phase, on days 1 and 22 of the maintenance cycle, and at any time point when the Absolute Neutrophil Count (ANC)/platelet count falls below the prescribed value until recovery. Cases of myelodysplastic syndromes and secondary malignancies, including myeloid leukemia, have been observed following administration of temozolomide. Patients receiving treatment may develop Pneumocystis pneumonia and patients should be offered prophylaxis during the concomitant phase of treatment and monitored during all phases. Serious hepatotoxicity has also been reported, and liver tests should be performed at baseline, midway through the first cycle, before each subsequent cycle, and approximately two to four weeks after the last dose.

The original drug of temozolomide has been launched in China and has entered the scope of Class B medical insurance. Common specificationsThe price of 100mg*1 pill*5 bags per box may be around 2,000 yuan. Domestic patients can use medical insurance for reimbursement when purchasing drugs in local hospitals or pharmacies. Due to different reimbursement ratios in different regions, the price after reimbursement may vary. The price of generic temozolomide drugs marketed overseas is relatively low, and its pharmaceutical ingredients are basically the same as those of the original temozolomide drug. For example, the price of a box of 100mg*5 produced by a Bangladeshi pharmaceutical factory may be around a few hundred yuan (the price may fluctuate due to exchange rates).