What are the side effects of Tafasitamab?

In clinical studies of tafasitamab as combination therapy, the most common (≥20%) adverse reactions were neutropenia, fatigue, anemia, diarrhea, thrombocytopenia, cough, pyrexia, peripheral edema, respiratory tract infection, and decreased appetite. Serious adverse reactions occurred in 52% of patients treated with tafracetamumab, including infection, pneumonitis, and febrile neutropenia. Fatal adverse reactions occurred in 5% of patients, including cerebrovascular accident, respiratory failure, progressive multifocal leukoencephalopathy, and sudden death.

69% of patients interrupted the dose of tafasitamumab or lenalidomide due to adverse reactions. The most common adverse reactions were blood and lymphatic system diseases and infections. Twenty-five percent of patients permanently discontinued tafasitamumab or lenalidomide due to adverse reactions, including infection, neurological disease, respiratory, thoracic, and mediastinal disease. Most clinically significant treatment-related adverse events are attributable to lenalidomide and can be managed with dose adjustment and supportive care. The lenalidomide dose may be reduced if necessary in patients who cannot tolerate the recommended dose. No dose adjustment is required for tafracetamumab in specific patient populations. If a patient experiences certain side effects, the doctor may stop treatment temporarily or permanently.

Talfaracetam's single-origin generic drug has not yet been launched in the country, so it is not included in medical insurance. There are European and American versions of Tafaracetam's single-antigen drugs marketed overseas. The American version's specificationsThe price per box of 200 mg may be around 20,000 yuan, and the price of the European version's 200 mg box may be around 10,000 yuan (the price may fluctuate due to exchange rates). The ingredients of the two drugs are basically the same, but the price is more expensive. Currently, there is no generic version of Tafaracetam on the market. For more drug information and specific prices, please consult a medical consultant.