Is Selinexor covered by Medicare?

Selinexor (Selinexor) is used with bortezomib and/or dexamethasone to treat multiple myeloma in adults and is also used in adults to treat certain types of diffuse largeB-cell lymphoma. Selinisol, which is usually given after other drugs don't work or stop working, was approved by the U.S. Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to selinesol, but further study is needed.

Selinesol is a first-in-class selective nuclear transport inhibitor (SINE) compound. Multiple myeloma, a cancer of antibody-producing plasma cells, is typically treated with high-dose chemotherapy with bortezomib and dexamethasone, followed by an autologous stem cell transplant. Other chemotherapy drugs for multiple myeloma include lenalidomide and dexamethasone, thalidomide, and, if the patient is not eligible for transplant, melphalan.

The original drug Seleniso has been marketed in China, but it has not yet entered the scope of medical insurance through the relevant policies of the National Medical Insurance Administration. Specifications The price of 20mg*12 tablets per box may be around RMB 20,000. The US version of the original Seleniso drug sold overseas, with a specification of 20mg*8 tablets, may cost more than 100,000 yuan per box (the price may fluctuate due to exchange rates), which is very expensive. Currently, there are also generic Selinisol drugs produced and marketed overseas. The price of a box of 20mg*16 tablets produced by a Lao pharmaceutical factory may be around RMB 4,000 (the price may fluctuate due to the exchange rate). Its drug ingredients are basically the same as those of the original drugs sold domestically and abroad.