How much does a box of Selinexor cost?

Selinexor (Selinexor) is a cancer drug used to treat multiple myeloma (a cancer of the bone marrow). It is used with two other drugs, bortezomib and dexamethasone, in adults who have had at least one previous treatment. It is also used with dexamethasone in adults who have had at least four previous treatments and whose condition has worsened since the last treatment. Selinisol is also indicated for adult patients with relapsed or refractory diffuse largeB-cell lymphoma who have received at least2 systemic therapies. Selinexor contains the active substanceselinexor, which blocks the action of a protein calledexportin 1 (XPO1). High levels of XPO1 are found in many cancer cells, where it blocks the action of certain proteins that help stop cancer growth. By blocking XPO1, selinexol enhances the action of these proteins, causing cancer cells to die, thereby slowing the progression of the disease.

The original drug Seleniso has been launched in China, but it has not yet entered the scope of medical insurance. The price of 20mg*12 tablets per box may be around 20,000 yuan, and the price of 20mg*16 tablets per box may be around 30,000 yuan. The US version of the original Seleniso drug sold overseas, with a specification of 20mg*8 tablets, may cost more than 100,000 yuan per box (the price may fluctuate due to exchange rates), which is very expensive. At present, there are also generic Seleniso drugs produced and marketed overseas, and the price is relatively cheap. For example, the price of 20mg*16 tablets per box produced by a Laos pharmaceutical factory may be around 4,000 yuan (the price may fluctuate due to the exchange rate). Its drug ingredients are basically the same as those of the original drugs sold domestically and abroad.