What should I do if I become drug-resistant after taking Selinexor?

If a patient develops drug resistance after taking Selinexor (Selinexor), first consult your doctor or oncologist who can evaluate the patient's specific resistance and help determine the next treatment plan. Resistance may mean that patients need to try other anti-cancer drugs or treatments. Doctors can recommend other suitable treatment options based on individual circumstances and conditions. Selinisol is currently approved for the treatment of multiple myeloma and diffuse large B-cell lymphoma, as a single agent or in combination with other drugs.

Depending on the patient's condition, the doctor may recommend a comprehensive treatment approach that combines many different medications and treatments to increase the effectiveness of the treatment. If a patient becomes resistant to selinesol, participating in a clinical trial may be an option. Clinical trials are studies of new treatments and drugs that provide patients with access to the latest treatments. If you agree to participate in a clinical trial, your doctor can provide information about suitable clinical trials.

The original drug Seleniso has been launched in China, but it has not yet entered the scope of medical insurance. Specifications The price of 20mg*12 tablets per box may be around 20,000 yuan. The US version of the original Seleniso drug sold overseas, with a specification of 20mg*8 tablets, may cost more than 100,000 yuan per box (the price may fluctuate due to exchange rates), which is very expensive. Currently, there are also generic Selinisol drugs produced and marketed overseas. The price of a box of 20mg*16 tablets produced by a Lao pharmaceutical factory may be around RMB 4,000 (the price may fluctuate due to the exchange rate). Its drug ingredients are basically the same as those of the original drugs sold domestically and abroad.