Have you ever used Ruxolitinib cream in China?

The original drug Ruxolitinib cream has not yet been marketed in China, so there are currently no reported cases of its use in the treatment of atopic dermatitis and vitiligo in China. However, the drug has begun to be used in clinical trials overseas and has achieved certain therapeutic effects. It is possible that ruxolitinib cream will be approved domestically and available to patients soon.

TwoPhase 3, double-blind, randomized, vehicle-controlled trials of hyperpigmentation treatment in patients with vitiligo produced similar results, showing1.5%Ruxolitinib creamThe primary endpoint and all key secondary endpointsof twice-daily treatment (Week 24) were statistically superior to vehicle cream, with approximately one-third of patients having an F-VASI75 response in facial pigmentation (the primary endpoint). Results for secondary endpoints are generally in the same direction as the results from the primary analysis. The percentage of patients meeting criteria for the primary and key secondary endpoints increased at Week 52, including patients who transitioned from vehicle to ruxolitinib cream at Week 28; however, due to the lack of adjustment for multiplicity, no clear conclusions can be drawn from these results. After 28 weeks of ruxolitinib cream treatment, efficacy in patients who switched to active treatment at week 52 was consistent with data at week 24 in patients who started ruxolitinib cream on day 1.

The price of ruxolitinib cream Original drug, specificationsinn 1.5%*60g, which is marketed overseas, is around RMB 20,000 per tube (the price may fluctuate due to the exchange rate), which is relatively expensive. The price of generic ruxolitinib cream marketed overseas is relatively cheap, and its pharmaceutical ingredients are basically the same as those of the original drug. The price of the specificationinn 1.5%*30g produced by a Bangladesh pharmaceutical factory is around 600 yuan per tube (the price may fluctuate due to exchange rate effects).