Is Ruxolitinib cream available in China?

Ruxolitinib cream is a selective Janus-activated tyrosine kinase inhibitor (JAK1 and JAK2) that mediates cytokine and growth factor signaling, which is important for hematopoietic processes and immune function. Janus kinase inhibitors down-regulate these inflammatory cytokines, which may be a useful mechanism of action in a variety of immune-mediated diseases, including atopic dermatitis and vitiligo.

Ruxolitinib cream is recommended for the treatment of atopic dermatitis by applying a thin layer to the affected area twice daily (<20% BSA); for the treatment of vitiligo, the dose is applied to the affected area in a thin layer twice daily (<10% BSA). Ruxolitinib Cream is not intended for use on >10% of body surface area (BSA) (Vitiligo) or >20% (atopic dermatitis), Do not use more than 60 grams per week or 100 grams every two weeks, and is not intended for oral, ophthalmic, or vaginal use. Concomitant use with otherJanus kinase inhibitors, biological therapies or immunosuppressants (such as cyclosporine, azathioprine) is not recommended. The risks of pregnancy are uncertain.

The original drug of ruxolitinib cream has not yet been launched in China and cannot be included in the medical insurance. Therefore, this drug is not currently sold in China. The price of ruxolitinib cream Original drug, specificationsinn 1.5%*60g, which is marketed overseas, is around RMB 20,000 per tube (the price may fluctuate due to the exchange rate), which is relatively expensive. The price of generic ruxolitinib cream marketed overseas is relatively cheap, and its pharmaceutical ingredients are basically the same as those of the original drug. The price of the specificationinn 1.5%*30g produced by a Bangladesh pharmaceutical factory is around 600 yuan per tube (the price may fluctuate due to exchange rate effects).