Fruquintinib Instructions

1. Indications:

Fruquintinib (Fruquintinib) is a multi-target small molecule tyrosine kinase inhibitor mainly used to treat patients with advanced gastric cancer or colorectal cancer whose disease has progressed after previous treatment with standard chemotherapy and trastuzumab.

2. Mechanism of action:

Fruquintinib blocks the blood supply of tumors and inhibits the growth of tumor cells by inhibiting multiple targets, including vascular endothelial growth factor receptors (VEGFR), epidermal growth factor receptors (EGFR), etc. Its multi-target mechanism of action gives it broad application prospects in tumor treatment.

3. Pharmacology:

The pharmacological characteristics of fruquintinib are mainly reflected in its inhibition of angiogenesis and blocking of tumor cell proliferation. This drug interferes with tumor blood vessel formation by regulating relevant signaling pathways, and at the same time directly acts on tumor cells to block their proliferation, thereby achieving therapeutic effects.

4. Dosage and usage:

The recommended dosage of fruquintinib is oral administration 1 times daily, 3 mg each time, continuous administration 4 weeks, and then discontinuation 1 weeks, forming a treatment cycle. Patients should follow the doctor's advice during medication and undergo regular examinations to monitor efficacy and adverse reactions.

5. Side effects:

Fruquintinib may cause a series of side effects, including but not limited to fatigue, loss of appetite, hypertension, hand-foot syndrome, etc. Patients should pay close attention to their physical condition during the medication, and inform their doctors promptly if they feel uncomfortable so that the treatment plan can be adjusted in a timely manner.

6. Warnings and precautions:

While using fruquintinib, patients should avoid using it at the same time with other drugs that may affect the cardiovascular system. Pay attention to regular blood pressure checks. If there are any abnormalities, they should seek medical treatment in time. In addition, pay special attention to the storage conditions of the medicine and avoid direct sunlight and humid environment.

7. Contraindications:

Contraindicated in patients allergic to fruquintinib components. Patients should report their allergic history to their doctor in detail before taking the medication to ensure that no serious allergic reaction will occur.

8. Drug interactions:

While taking fruquintinib, patients should avoid adverse interactions with other drugs. It should be under the guidance of a doctor to avoid concurrent use with drugs that may increase cardiovascular risks, such as nonsteroidal anti-inflammatory drugs.

9. Medication for special groups:

For pregnant and lactating women, as well as elderly patients and patients with renal insufficiency, fruquintinib should be used under physician supervision. During the medication period, relevant biochemical indicators and organ functions should be monitored regularly to ensure safe and effective treatment.

10. Listing and price situation:

Fruquintinib is a drug developed in Hong Kong, China. It has been approved for marketing by the State Food and Drug Administration and has been included in medical insurance. Patients can buy it in domestic hospital pharmacies at a price of about one to two thousand. For specific prices, please consult the local hospital pharmacy.

Overall, fruquintinib is a drug with potential value in the treatment of advanced gastric cancer or colorectal cancer. Patients should carefully follow the doctor's recommendations when using it and pay close attention to their own conditions to ensure the safety and effectiveness of the treatment.