What are the side effects of Semaglutide?

Like all drugs in the GLP-1 receptor agonist class, the adverse reactions of oral Semaglutide tablets are not related to the gastrointestinal tract. The most common adverse reactions are nausea, vomiting, diarrhea and hypoglycemia. After Semaglutide tablets were put on the market, adverse events such as intestinal obstruction, allergic reactions, angioedema, rash, urticaria, cholecystitis, and gallstones (requiring cholecystectomy) have also occurred. While oral administration is a potential advantage of this product, current dosing recommendations may cause difficulties for some patients.

Over time, people with diabetes and high blood sugar may develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Medications, lifestyle changes (such as diet, exercise, quitting smoking), and regular blood sugar checks may help control diabetes and improve your health. In clinical studies of semaglutide tablets, warnings and precautions have also emerged regarding the risk of thyroid C-cell tumors, pancreatitis, complications of diabetic retinopathy, hypoglycemia with the use of insulin secretagogues or insulin, acute kidney injury, hypersensitivity reactions, acute gallbladder disease, etc.

Semaglutide tablets have not yet been launched in China. Its injection has been launched in China and is covered by medical insurance, but only eligible patients can be reimbursed.The price of each 3ml tube may be around RMB 1,000. The original drug Semaglutide tablets sold overseas, with a specification of 3 mg*100 tablets, may cost around 2,000 yuan per box (the price may fluctuate due to exchange rates). There are currently no generic versions of semaglutide on the market.