Manufacturer of Pirfenidone

Pirfenidone (Pirfenidone) The drug was developed by multiple companies around the world, including original patent holder Marnac, InterMune (now part of Roche), Shionogi and GNI Group. Pirfenidone is derived from pyridone and is synthetic. It is an anti-fibrotic and anti-inflammatory agent commonly used in cases of idiopathic pulmonary fibrosis (IPF).

Pirfenidone reduces the production of transforming growth factor-β1 (TGF-β1), a profibrotic and proinflammatory cytokine associated with idiopathic pulmonary fibrosis. By inhibiting TGF-β1, it also inhibits the conversion of fibroblasts into myofibroblasts in human lungs, thereby preventing collagen synthesis and extracellular matrix production. Pirfenidone is available as an oral capsule or tablet. It is usually taken three times a day with food, at about the same time each day. It may be used as a first-line medication with nintedanib. Some common side effects of pirfenidone include gastrointestinal disturbances, diarrhea, rash, nausea, and vomiting.

The original drug pirfenidone has been approved for marketing in China and has entered the scope of Class B medical insurance. Reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 100mg*54 tablets is about 500 yuan. There are also generic pirfenidone drugs produced in other countries overseas. For example, the price of a box of 200mg*30 tablets produced by an Indian pharmaceutical factory is around RMB 100 (the price may fluctuate due to the exchange rate). The ingredients of the generic drugs are basically the same as those of the original drug. For more drug information and specific prices, please consult Yaode Medical Consultant.