The difference between Indian and domestic pirfenidone

Pirfenidone (Pirfenidone) is a drug mainly used to treat idiopathic pulmonary fibrosis. It slows down the progression of the disease by inhibiting inflammation and fibroblast activity in the fibrosis process. Pirfenidone produced by Indian pharmaceutical companies and pirfenidone (domestic drug) produced by Chinese pharmaceutical companies are both generic versions of pirfenidone. The original drug pirfenidone has also been approved for marketing in China and has entered the scope of Class B medical insurance, with reimbursement limited to patients who meet the indications.

Pirfenidone is an orally administered small molecule with anti-inflammatory and anti-fibrotic effects. In animal models, it leads to dose-related reductions in fibrosis through modulation of cytokines and growth factors, including transforming growth factor-β and tumor necrosis factor-α. Indian pirfenidone and domestic pirfenidone should be chemically identical as they are based on the same active ingredient and should have similar effects in treating idiopathic pulmonary fibrosis. However, there may be some subtle differences between the two, such as manufacturing process, drug purity, additives, etc. In addition, the price of Indian pirfenidone and domestic pirfenidone may be different. Domestic drugs are often cheaper than imported drugs due to patent protection and market competition.

Pirfenidone Original drug, which is marketed in China and has entered medical insurance, the price of 100mg*54 tablets per box may be around 500 RMB, and the price of domestically produced drug 200mg*9 tablets*3 tablets per box may be around 700 RMB. Common Indian pharmaceutical companies include Cipla Pharmaceuticals, Bruvver Pharmaceuticals, etc. The price of each box of 200mg*30 tablets is around 100 yuan (the price may fluctuate due to the exchange rate). For more drug information and specific prices, please consult Yaode Medical Consultant.