Price of Upadacitinib

Upadacitinib (Upadacitinib) is a Janus kinase (JAK) inhibitor indicated for the treatment of rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn's disease, ankylosing spondylitis, and nonradiographic axial spondyloarthritis. Upadatinib is available as an extended-release tablet that may be taken by mouth once daily.

Upadatinib works by blocking the activity of Janus kinase in theJAK-STAT signaling pathway, an intracellular pathway that plays a major role in the release of pro-inflammatory cytokines that stimulate inflammation in rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn's disease, ankylosing spondylitis, and non-radiographic axial spondyloarthritis. Common side effects include upper respiratory tract infections such as the common cold and sinus infections, nausea, cough, and fever. Weight gain, rosacea, and acne have also been reported in patients.

The original drug Upatinib has been launched in China, and has subsequently entered the scope of Class B medical insurance. Only eligible patients can be reimbursed. Specifications The price of each box of 15mg*28 tablets may be around RMB 3,000. The European version of the original drug sold overseas is priced at more than 20,000 yuan for 15mg*30 tablets (the price may fluctuate due to exchange rates), which is expensive. Cheaper upadatinib generic drugs are also sold overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 15mg*30 tablets produced by Bangladesh pharmaceutical factory is around 900 yuan (the price may fluctuate due to the exchange rate).