How many years should you take Crizotinib?

The length of time Crizotinib should be used will depend on the patient's condition and the doctor's advice. In some cases, patients may need to take crizotinib long-term, possibly even for several years. However, the treatment period varies from person to person, and each patient's situation is unique, so when using crizotinib, it is best to follow the doctor's guidance and conduct regular examinations and consultations to ensure the effectiveness and safety of the drug.

Crizotinib is available in capsule form. The recommended dose for adults with ALK-positive or ROS1-positive advanced non-small cell lung cancer is 250 mg twice daily. The recommended dose for children and adolescents with ALK-positive ALCL or ALK-positive IMT is based on body surface area (calculated based on the patient's height and weight). If certain side effects occur, your doctor may decide to interrupt or reduce the dose. If a patient develops certain serious side effects, treatment may have to be stopped completely. Dosage adjustments may be required in patients with severely reduced renal or hepatic function.

The original drug Crizotinib has been launched in China and is covered by medical insurance, but it is only reimbursed for patients who meet the indications. The price per box may be around RMB 15,000. The price of the original Turkish version of Crizotinib sold overseas may be more than RMB 10,000 per box (the price may fluctuate due to exchange rates), which is expensive. There are also cheaper generic crizotinib drugs available overseas. The ingredients are basically similar to those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by a Bangladesh pharmaceutical factory may be more than 2,000 yuan per box (the price may fluctuate due to exchange rates).