How effective is Nintedanib in treating pulmonary fibrosis?

Nintedanib(Nintedanib)sold under the trade names Ofev and Vargatef is an oral drug used to treat idiopathic pulmonary fibrosis and, with other drugs, certain types of non-small cell lung cancer. How effective is Nintedanib(Nintedanib) in treating pulmonary fibrosis?

A Phase 2 trial showed that nintedanib at 150 mg twice daily reduced lung function decline and exacerbations in patients with idiopathic pulmonary fibrosis. A total of 1066 patients were randomly assigned in a 3:2 ratio to receive nitannib or placebo. In FVC, the adjusted annual rate of change in the nintedanib group was -114.7ml compared with -239.9ml(the difference was The nintedanib group was -1 and -113.6ml, while the placebo group was -207.3ml(The difference was 93.7< span>ml; 95%confidence interval is 44.8 to 142.7; P<0.001) in input. In sis-1, there was no significant difference in time to first acute exacerbation between the nintedanib group and the placebo group (the hazard ratio in the nintedanib group was 1.15; pan>95%The confidence interval is 0.54 to 2.42; p = 0.67); ininput In sis-2, nintedanib had a significant benefit compared with placebo (hazard ratio 0.38; 95 %The confidence interval is 0.19 to 0.77; P=0.005). In patients with idiopathic pulmonary fibrosis, nintedanib reduced the decline in FVC, consistent with slowing disease progression. There are generic drugs in India that are already on the market, and each box costs about 4 around 100. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.