Is Palbociclib a capsule?

Palbociclib (Palbociclib) is a medicine usually available in opaque hard gelatin capsules. Oral palbociclib capsules contain 125 mg, 100 mg, or 75 mg of the kinase inhibitor palbociclib, whosemolecular formula isC24H29N7O2. When the pH value is ≤ 4, palbociclib appears as a highly soluble compound; when pH> 4, the solubility of the drug is significantly reduced.

Palbociclib is a targeted therapy drug that is a CDK4/6 inhibitor. CDK4/6 represents cell cycle regulatory protein-dependent kinases 4 and 6. These kinases play an important role in the process of cell inhibition. Palbociclib 125 mg capsules have a caramel-colored capsule cap and capsule body, with "Pfizer" printed in white ink on the capsule cap, and "PBC 125" printed on the capsule body; 100 mg capsules have a caramel-colored capsule cap and light orange capsule body, with "Pfizer" printed in white ink on the capsule cap, and "PBC" printed on the capsule body The 100" 75 mg capsule has a light orange capsule cap and capsule body, with "Pfizer" printed in white ink on the capsule cap and "PBC 75" printed on the capsule body.

PalbociclibThe original drug has been launched in China and has been included in medical insurance. Currently, reimbursement is only available to patients who meet the indications. The common specifications100mg*21 pills may cost more than 6,000 yuan per box, while the original drug sold overseas is more expensive. The price of 125mg*21 pills per box may be around 10,000 yuan (the price may fluctuate due to exchange rates). Palbociclib generics are also sold overseas. The ingredients of the drug are basically the same as those sold domestically and abroad, but the price is cheap. For example, the price of a box of 125mg*21 tablets produced by a Bangladesh pharmaceutical factory may be several hundred yuan (the price may fluctuate due to the exchange rate).