Palbociclib side effects

Palbociclib (Palbociclib) is mainly used for the treatment of breast cancer. It is often used in combination with other drugs such as estrogen receptor agonists to treat estrogen receptor-positive (ER+) breast cancer. The use of palbociclib can prolong progression-free survival and improve treatment efficacy. Not all patients will experience these side effects, and the severity and duration of side effects vary from person to person.

The most common side effects of palbociclib are neutropenia (low levels of neutrophils in the blood, which are infection-fighting white blood cells), infection, leukopenia (low white blood cell count), fatigue, nausea (feeling sick), stomatitis (inflammation of the mucous membranes in the mouth), anemia (low red blood cell count), diarrhea, alopecia (hair loss), and thrombocytopenia (low platelet count). The most common serious side effects are neutropenia, leukopenia, infection, anemia, fatigue, and increased blood levels of liver enzymes (aspartate ALT and alanine aminotransferase AST).

PalbociclibThe original drug has been launched in China and has been included in medical insurance. Currently, reimbursement is only available to patients who meet the indications. The common specifications100mg*21 pills may cost more than 6,000 yuan per box, while the original drug sold overseas is more expensive. The price of 125mg*21 pills per box may be around 10,000 yuan (the price may fluctuate due to exchange rates). Palbociclib generics are also sold overseas. The ingredients of the drug are basically the same as those sold domestically and abroad, but the price is cheap. For example, the price of a box of 125mg*21 tablets produced by a Bangladesh pharmaceutical factory may be several hundred yuan (the price may fluctuate due to the exchange rate).