What kind of medicine is MITOTANE?

Mitotane (MITOTANE) is an antineoplastic drug indicated for the treatment of inoperable functional and non-functional adrenocortical carcinomas. Mitotane is currently the only drug approved for adrenocortical cancer.

The structure of Mitotane is similar to the insecticides DDT and DDD, which can cause atrophy and necrosis of the adrenal cortex. After taking the drug, the levels of adrenocortical hormones and their metabolites in the body can be rapidly reduced, and it can be used to treat Kewpie syndrome caused by adrenal tumors or adrenal hyperplasia.

Follow all directions on the prescription label when taking mitotane, and read all medication guides or inserts. Your doctor may occasionally change the dose, just follow the directions. Patients may need frequent medical exams and even if they do not have symptoms, testing can help doctors determine if mitotane is effective. Patients may need to take steroid medications or stop taking mitotane for a short time if a serious injury or medical emergency occurs. Your doctor will decide when you can start taking this medicine again. Do not change your dosage or medication schedule without your doctor's advice. You must receive medical attention while taking mitotane. Storemitotane at room temperature, away from moisture and heat. Ifthe patient misses a dose, take the dose as soon as possible, but if it is time for the next dose, skip the missed dose and do not take two doses at once. You should avoid driving or hazardous activities while taking mitotane and avoid activities that may increase the risk of bleeding or injury.

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