Avatrombopag usage and dosage
Avatrombopagis a platelet-raising drug indicated for the treatment of thrombocytopenia in adults with chronic liver disease who are scheduled to undergo surgery and for the treatment of thrombocytopenia in adults with chronic immune thrombocytopenia(ITP)who have had an inadequate response to previous therapy.

For patients with chronic liver disease and platelet count below40 x 10(9)/L: 60 mg orally daily starting 10 to 13 days before scheduled surgery. Platelet count40to less than50 x 10(9)/L: 40 mg, PO, once daily, starting 10 to 13 days before scheduled surgery. The duration treatment is 5 days.
For chronic immune thrombocytopenia: Initial dose is 20 mg once daily with food, Maximum dose: 40mg/day.
In the event that a dose is missed, take the next dose as soon as possible and do not take two doses at once to make up for the missed dose. The next regularly scheduled dose should be administered at the usual time the next day. For patients with chronic liver disease, check platelet counts before starting medication and on the day of surgery. For patients with chronic immune thrombocytopenia, the platelet count should be tested once a week until the stable platelet count is greater than or equal to 50 x 10(9)/L, then once a month, and once a week after drug withdrawal, for at least 4 weeks.
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