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Avatrombopag is a platelet stimulator indicated for the treatment of thrombocytopenia in patients with chronic liver disease scheduled for surgery. Also used to treat thrombocytopenia in patients with chronic immune thrombocytopenia who have had an inadequate response to prior therapy.

For chronicITP patients, side effects include headache(31%), fatigue(28% ), contusion(26%), nosebleed(19%), upper respiratory tract infection(15%), joint pain(13%), gum bleeding(13%), petechiae (11%), nasopharyngitis (10%), headache (1.6%), etc.

For patients with chronic liver disease, side effects include abdominal pain(6-7%), nausea(6-7%), fatigue(3-4%), and peripheral edema

Advise women not to breastfeed during treatment and for at least2 weeks after the last dose. If this drug is used short-term in nursing mothers (i.e. before treatment in patients with chronic liver disease), it is recommended to interrupt breastfeeding and discard the affected breast milk during treatment and for 2 weeks after the last dose. According to animal experiments, it may cause harm to the fetus. There are insufficient human data and adverse developmental outcomes have been observed in animal studies at exposure doses substantially higher than the maximum human doses.

Inform pregnant women of fetal risks.

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