The latest price of dabrafenib in 2024 is released. How much can patients buy a box?

Dabrafenib, used alone or in combination with another drug called tramatinib, is used to treat certain types of cancer in people who have the BRAF gene mutation. Dabrafenib is used to treat melanoma (skin cancer) that cannot be treated with surgery or has spread to other parts of the body, or to prevent melanoma from coming back after surgery; or non-small cell lung cancer that has spread to other parts of the body; or advanced or metastatic thyroid cancer that has spread and there are no other treatment options.

Dabrafenib Active substancedabrafenib works by blocking BRAF, a protein involved in stimulating cell division. In melanoma and non-small cell lung cancer with BRAF V600 mutations, abnormal forms of BRAF play a role in the development of the cancer by allowing tumor cells to divide uncontrollably. By blocking the action of abnormal BRAF, dabrafenib helps slow the growth and spread of cancer.

The original drug of dabrafenib is relatively expensive. It has been included in the scope of medical insurance after being launched in China. Currently, it is only available for reimbursement to eligible patients. The price of each box of 50mg*120 tablets may be around 10,000. The Turkish version of dabrafenib original drug sold overseas, with a specification of 75mg*120 pills, may cost around 10,000 per box (the price may fluctuate due to exchange rates). There are also cheaper generics of dabrafenib sold overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of a box of 75mg*120 tablets produced by a Lao pharmaceutical factory may be more than 4,000 yuan (the price may fluctuate due to exchange rates).