Where can I buy the latest dabrafenib in China?

Dabrafenib is a competitive and selective BRAF inhibitor that binds to the ATP pocket. Although dabrafenib inhibits wild-type BRAF, it has higher affinity for mutant forms of BRAF, including BRAF V600E, BRAF V600 K, and BRAF V600 D. BRAF is a serine/threonine protein kinase involved in activating the RAS/RAF/MEK/ERK or MAPK pathway, a pathway related to cell cycle progression, cell proliferation, and prevention of apoptosis. Accordingly, constitutively active mutations in BRAF, such as BRAF V600E, are frequently observed in many types of cancer, including melanoma, non-small cell lung cancer, thyroid cancer, and colon cancer.

The original drug of dabrafenib is relatively expensive and has been covered by medical insurance since it was launched in China. Currently, it is only available for reimbursement to eligible patients. The price of each box of 50 mg*120 pills may be around RMB 10,000. This drug may be sold in local hospitals or pharmacies. Patients can purchase this drug with the doctor's prescription information. The Turkish version of the original drug Dabrafenib sold overseas, Specifications 75mg*120 capsules, may cost around 10,000 per box (the price may fluctuate due to exchange rates). There are also relatively cheap generics of dabrafenib sold overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, Specifications produced by Laos Pharmaceutical Factory The price of 75mg*120 tablets per box may be more than 4,000 yuan (the price may fluctuate due to exchange rates). For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.