The latest price for dabrafenib combined with trametinib is released

The combination of dabrafenib and trametinib is indicated for the treatment of BRAF V600E or V600K mutation-positive unresectable or metastatic melanoma and its postoperative adjuvant therapy. It can also be used to treat patients with BRAF V600E mutation-positive metastatic non-small cell lung cancer, locally advanced or metastatic anaplastic thyroid cancer, unresectable or metastatic solid tumors, and low-grade malignant glioma. The recommended dose of dabrafenib is 150 mg in 50 or 75 mg capsules twice daily. The recommended dose of trametinib is 2 mg once daily as a 0.5, 1 or 2 mg tablet.

The original drug of dabrafenib is relatively expensive and has been covered by medical insurance since it was launched in China. Currently only eligible patients are reimbursed. The price of each box of 50mg*120 capsules may be around around 10,000. The Turkish version of the original drug Dabrafenib sold overseas, Specifications 75mg*120 capsules, may cost around 10,000 per box (the price may fluctuate due to exchange rates). There are also relatively cheap generics of dabrafenib sold overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, Specifications produced by Laos Pharmaceutical Factory The price of 75mg*120 tablets per box may be more than 4,000 yuan (the price may fluctuate due to exchange rates).

The original drug of trametinib has also been launched in China and has been included in the scope of medical insurance. The price of 2 mg*30 tablets is around RMB 20,000. The original drug of trametinib sold overseas, specification is priced at about RMB 10,000 for 2 mg*30 tablets (the price may fluctuate due to exchange rates). There are also generic drugs produced in other countries overseas. For example, the price of generic drugs Specification 2mg*30 tablets produced by Laos pharmaceutical factory is 3,000 yuan (the price may fluctuate due to the exchange rate). The high price may increase the financial burden on some families, but the price of generic drugs is lower than the original ones.