Has selumetinib been included in medical insurance?

On Year4Month10, the US Food and Drug Administration approved selumetinib (AstraZenecaKOSELUGO)for2 Pediatric patients years of age and older with neurofibromatosis type 1(NF1) who have symptomatic, inoperable plexiform neurofibromatosis(NF1)

Selumetinib was launched in China on April 28, 2023 and has not yet been included in medical insurance. The retail price of selumetinib in domestic pharmacies10mg60 tablets is about 23,600 yuan. There is an original research version overseas, with a retail price of around 10mg60 tablets50,000.

SelumetinibCommon side effects are headache, nausea, vomiting, abdominal pain, diarrhea, and fatigue, Musculoskeletal pain(Body pain affecting bones, muscles, ligaments, tendons, and nerves), fever, dry skin, acneiform rash(Acne)and other rashes, Stomatitis(Inflammation of the mouth and lips), paronychia(Skin infection)and itching(itch) around the toenails or fingernails. Selumetinibcan also cause serious side effects, including heart failure (manifested by reduced ejection fraction, or when the muscles in the heart’s left ventricle do not pump blood as well as normal) and eye toxicity(Acute and chronic damage to the eyes)Including retinal vein occlusion, retinal pigment epithelial separation and impaired vision. Selumetinib also causes creatinine phosphokinase (CPK) . CPK is an enzyme found in the heart, brain, and skeletal muscles. CPK can leak into a person's bloodstream when muscle tissue is damaged, which may be rhabdomyolysis (the breakdown of skeletal muscle due to direct or indirect muscle damage). Additionally, selumetinibcapsules contain tocopherol, which may increase a user's risk of bleeding if their daily intake of vitaminE exceeds recommended or safe limits. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.