Symptoms corresponding to Sotorasib side effects

Sotorasib is a targeted therapy for non-small cell lung cancer with KRAS G12C mutations. Although it may significantly improve the patient's condition during treatment, it may also cause some side effects. Here are some possible side effects and their corresponding symptoms:

1. Fatigue: Patients may feel persistent fatigue and weakness. Get enough rest and sleep, exercise moderately, and report severe fatigue to your doctor.

2. Nausea and vomiting: May be accompanied by nausea, loss of appetite, and even vomiting. Eat in portions and avoid spicy and greasy foods. If symptoms persist, you should consult a doctor in time.

3. Diarrhea: Diarrhea may occur, affecting quality of life. Maintain adequate fluid intake, avoid overly spicy or irritating foods, and consult your doctor for appropriate treatment.

4. Skin rash and skin reactions: Skin reactions such as rash, itching, and dryness may occur. Use gentle skin care products, avoid exposure to strong sunlight, and notify your doctor of symptoms.

5. Eye problems: May cause dry eyes, pain, blurred vision and other problems. Use artificial tears to relieve dry eyes and report any eye discomfort to your doctor promptly.

6. Muscle pain: It may be accompanied by muscle pain and joint pain. Rest, exercise moderately, and report pain to your doctor.

7. Others: May include headache, loss of appetite and other general discomfort symptoms. Take appropriate symptomatic treatment according to specific symptoms and consult your doctor for advice in a timely manner.

Patients should maintain close contact during medication and promptly report any symptoms of discomfort to the doctor so that the doctor can make timely adjustments and management.

The original drug of sotorasibu has not yet been launched in China, so patients cannot purchase it domestically and need to purchase sotorasibu through overseas channels. The price of the original version of sotorasibu in Hong Kong, China, with the specifications of 120mg*240 tablets, is around 8 million, and the price of the European version of the original drug with the same specifications is around 4 million, which is relatively expensive. The cheaper ones are the generic drugs marketed abroad. For example, the price of generic drugs in Laos and Bangladesh is around two to three thousand yuan. The price is relatively cheap, and the ingredients of foreign generic drugs are basically the same as the original drugs.