What are the food taboos while taking everolimus? What should I pay attention to?
Everolimus is the mammalian target of rapamycin (mTOR) kinase inhibitor and is used to treat various types of malignant tumors. Everolimus is a derivative of rapamycin(sirolimus) that acts similarly to the mTOR (mammalian target of rapamycin) inhibitor of rapamycin. Everolimus is used as an immunosuppressant to prevent rejection of organ transplants. Similar to other mTOR inhibitors, everolimus only targets the mTORC1 protein, not the mTORC2 protein.

What are the taboo foods when using everolimus(everolimus)?
1. Avoid grapefruit and grapefruit juice. Grapefruit and grapefruitjuice can increase blood concentration and efficacy. Avoid ingesting grapefruit and grapefruit juice while taking everolimus.
2. Avoid the intake of irritating foods, such as chili peppers. Chili peppers can irritate the gastrointestinal tract and affect the efficacy of everolimus. Avoid consuming irritating foods while taking everolimus.
3. Avoid seafood. When taken at the same time, it may affect the absorption of the gastrointestinal tract and may reduce the efficacy of the drug. Avoid ingesting seafood at the same time.
4. Reduce the intake of high-fat foods, such as cakes, fatty meats, etc. It may cause hyperlipidemia, so avoid taking high-fat foods at the same time while taking it.
What should I pay attention to when taking everolimus?
1.May causenon-infectious pneumonia: Monitor for clinical symptoms or radiological changes, withhold or permanently discontinue based on severity.
2.PossibleInfection: Monitor for signs and symptoms of infection and withhold or permanently discontinue based on severity.
3.Possibility ofSevere allergic reactions:For clinically significant allergic reactions, the drug should be permanently discontinued. •
4.Possibility ofAngioedema:Patients taking concomitant angiotensin-converting enzyme(ACE) inhibitors may be at increased risk for angioedema and permanent discontinuation due to angioedema.
5.Possibility ofstomatitis:When starting treatment, start using dexamethasone alcohol-free mouthwash.
6.Possible occurrenceKidney failure:Monitor kidney function regularly before and after treatment.
7.Possiblerisk of impaired wound healing:Withhold medication for at least 1 weeks before elective surgery. Do not administer this medication for at least 2 weeks after major surgery until the wound has completely healed. The safety of resuming treatment after resolution of wound healing complications has not been established.
8.May occurmetabolic disorders:Regularly monitor blood sugar and blood lipids before and after treatment, withhold or permanently stop based on severity.
9.Possible occurrenceMyelosuppression:Monitor hematological parameters regularly before and after treatment, Withhold or permanently stop based on severity.
10.Vaccination carries the risk of infection or reduced immune response:Avoid receiving live vaccines and avoid close contact with people who have received live vaccines. Complete recommended childhood vaccinations before starting treatment.
11.Radiation allergy and radiation recall:Severe radiation reactions can occur.
12.Embryo-Fetal Toxicity:Can cause fetal harm. Inform patients of reproductive potential of potential risks to the fetus and use effective contraception.
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