What should not be taken while taking bedaquiline and what are the side effects?

Bedaquiline (Bedaquiline) is a drug used to treat tuberculosis. When taking this drug, some foods and drugs may affect its efficacy or cause side effects, including some skin reactions, liver damage, visual problems, nausea, headache, dizziness, etc. If serious side effects or symptoms occur, you should stop taking bedaquiline immediately and consult a doctor. Here are some things to note:

1. Avoid drinking alcohol: Alcohol may interact with bedaquiline and affect its metabolism and efficacy. Therefore, you should avoid drinking alcohol while taking bedaquiline.

2. Avoid high-fat foods: High-fat foods may affect the absorption and metabolism of bedaquiline, so you should avoid eating too much high-fat foods.

3. Avoid simultaneous use with certain drugs: Some drugs may interact with bedaquiline, such as rifamycins (i.e., rifampicin, rifapentine, and rifabutin), causing adverse effects. Therefore, concomitant use of other drugs, especially those with hepatotoxicity, should be avoided while taking bedaquiline.

The drug is sold in China under the name of daquiline fumarate tablets and has been included in the scope of medical insurance. The price of a common specification of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The price of the Russian version of Bedaquiline sold overseas, Specifications100mg*188 tablets per box, may be around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of Bedaquiline sold domestically and abroad are basically the same. Currently, there are no generic bedaquiline drugs produced and marketed overseas. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.