shock! Is the price of domestic bedaquiline 8,400 true?

Currently, there is no domestically produced bedaquiline (Bedaquiline) on the market in China. The domestically produced bedaquiline is an imported drug produced by Johnson & Johnson. The U.S. Food and Drug Administration (FDA) has approved a new drug, bedaquiline, a diarylquinoline drug for the treatment of multidrug-resistant tuberculosis.

Major problems with existing anti-tuberculosis drugs used to treat MDR-TB are antimicrobial resistance, low efficacy and poor side effects. Bedaquiline may be the solution to these problems. Bedaquiline is the first drug of its kind with a unique and specific mechanism of action. It inhibits the proton pump of mycobacterial adenosine triphosphate (ATP) synthase. There are a number of randomized clinical trials and cohort studies reporting higher culture conversion rates in bedaquiline-treated groups compared with control groups. Many meta-analyses and systematic reviews have reported higher culture conversion rates, higher cure rates, and lower mortality in drug-resistant TB patients treated with bedaquiline-line regimens.

The drug is sold in China under the name of daquiline fumarate tablets and has been included in the scope of medical insurance. The price of a common specification of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The price of the Russian version of Bedaquiline sold overseas, Specifications100mg*188 tablets per box, may be around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of Bedaquiline sold domestically and abroad are basically the same. Currently, there are no generic bedaquiline drugs produced and marketed overseas. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.