I already know the news! Is bedaquiline a national free drug? How do patients apply?

Bedaquiline (Bedaquiline) is not a free national drug. However, there are ways for patients to request free or low-cost bedaquiline. Specifically, some countries or regions may include bedaquiline on the list of free drugs in the public health system so that patients can obtain free or subsidized drugs when needed. Several international organizations and NGOs are also working to provide free or low-cost supplies of bedaquiline to help patients who cannot afford the expensive drug.

Bedaquiline, the first drug of its kind that could help better manage tuberculosis, was discovered by scientists at Johnson & Johnson's Janssen pharmaceutical division. Bedaquiline has unique and specific antimycobacterial activity. It inhibits the proton pump of mycobacterial adenosine triphosphate (ATP) synthase. This is done with the help of ATP synthase. BedaquilineinhibitsATP production. The binding affinity of bedaquilineto mycobacterialATP synthase is more than 20,000 times higher than its binding affinity to human mitochondrial ATP synthase. This has a specific role only in mycobacteria and causes minimal damage to host cells.

The drug is sold in China under the name of daquiline fumarate tablets and has been included in the scope of medical insurance. The price of a common specification of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The price of the Russian version of Bedaquiline sold overseas, Specifications100mg*188 tablets per box, may be around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of Bedaquiline sold domestically and abroad are basically the same. Currently, there are no generic bedaquiline drugs produced and marketed overseas. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.