How effective is the Lao version of mitotane?

Mitotane (Mitotane) The original drug has been launched in many countries. It is understood that there are also many overseas countries producing generic versions of Mitotane. Its pharmaceutical ingredients are basically the same as those of the original drug. It is often used to treat functional or non-functional, inoperable adrenocortical cancer. It acts on the part of the body called the adrenal cortex and can reduce the amount of steroids produced by the adrenal cortex. There may be slight differences in production specifications and prices.

Mitotane is poorly understood and its biochemical mechanism is unclear. This is an oral chemotherapy drug. Although it can cause adrenal suppression, it apparently does not destroy cells. Administration of mitotane alters extra-adrenal cortisol metabolism in humans, resulting in a significant decrease in17-hydroxycorticosteroids. Although there is no decrease in plasma levels of corticosteroids, the drug significantly increases the formation of 6-B-hydroxycorticosteroids. Mitotane can be used in combination with chemotherapy drugs, and etoposide-doxorubicin-cisplatin combined with mitotane (EDP-M) will be the first-line treatment.

The original drug of mitotane has been launched in China, but it has only been on the market for a short time, its purchase is very difficult, and it is not included in medical insurance. Mitotane marketed overseas The original drug has European and Turkish versions, specificationsThe price of 500mg*100 tablets per box may be more than 9,000 yuan (the price may fluctuate due to exchange rates). The specifications of mitotane generic drugs produced by Lao pharmaceutical factories sold overseasThe price of each box of 500mg*100 tablets may be more than 3,000 yuan (the price may fluctuate due to the exchange rate). For specific prices and drug details of overseas drugs, please consult Yaode Medical Consultant.