Capmatinib launch date
Capmatinibon2020year5month6Approved by the U.S.FDA for listing, capmatinib will be launched in China in July of 2021. Capmatinib is a kinase inhibitor targeting the c-Met receptor tyrosine kinase and is indicated for the treatment of Met exon 14 skipped non-small cell lung cancer.

A patient treated withcapmatinib developed fatalILD/pneumonitis. 4.8%of patients receiving capmatinib with geometrymono-1 developed ILD/pneumonitis, 1.9% patients developed grade ILD/ pneumonia, and 1 patient died (0.3%). Nine patients (2.4%) discontinued Taibida due to ILD/pneumonitis. The median time to onset of grade 3 or higher ILD/pneumonia was 1.8 months (range : 0.2 months to 1.7 years). Monitor for new or worsening symptoms of ILD/pneumonia (e.g., difficulty breathing, cough, fever). For patients with suspected ILD/pneumonia, discontinue this product immediately, or permanently if no other potential causes of ILD/pneumonia are found. Hepatotoxicity occurred in patients receivingcapmatinib. 15%Accept geometric shapesmono-1's Capmatinib-treated patients experienced an increase in alanine aminotransferase (ALT) /aspartate aminotransferase (AST). 7%of patients had ALT/AST grade 3 or 4 grade elevation. Three patients (0.8%) discontinued capmatinib due to ALT/AST elevations. The median time to onset of grade 3 or higher ALT/AST elevations was 1.8 months (range: 0.5 to 46.4 months). Before starting capmatinib, monitor liver function tests (including
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