Axitinib/Axitinib (Axitinib) effects and efficacy

Axitinib is an oral VEGFR and kinase inhibitor indicated for the treatment of advanced renal cell carcinoma (RCC) after failure of prior systemic therapy. Axitinib is a second-generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumor growth and metastasis. It is reported to be 50-450 times more potent than first-generation VEGFR inhibitors. Axitinib is an indazole derivative. It is commonly marketed as Inlyta and is available as an oral preparation.

54%(95% CI: 40–67) of patients in the axitinib titration group and 34%(95%) of patients in the placebo group CI: 22–48) had an objective response (unilateral P=0.19), compared with 59% of nonrandomized patients (95% CI: 49–70). Sometimes it is unsafe to use certain drugs together. Some medicines can affect the blood levels of other medicines you take, which may increase side effects or make the medicine less effective. Other drugs may affect axitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all the medicines you currently take and any medicines you start or stop using. Overseas generic drugs are available in Bangladesh, and the retail price of Bangladeshi Beacon Pharmaceutical is about 5mg 60 tablets 1800 yuan. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.