How effective is Eltrombopag/Eltrombopag treatment? Are there any serious side effects?

In one study, the effect of adding eltrombopag to immunosuppressive therapy was significant in the treatment of patients with severe aplastic anemia. Ninety-two consecutive patients were enrolled in this study. Three consecutively enrolled cohorts differed in timing of initiation and duration of the eltrombopag regimen(Cohort1from /span>14 days to6months receiving eltrombopag, cohort2From day 14 to 3 month, queue 3From 1day to 6month). These cohorts were analyzed separately. The primary outcome was complete hematologic response at 6 months. Secondary endpoints include overall response, survival, recurrence, and clonal evolution in medullary carcinoma.

Results:The complete response rate of the 1 group at 6 months33%< span>, the 2 group was 26%, and the 3 group was 58%. Overall response rates at 6 months were 80%, 87%, and 94%, respectively. The complete response rate and overall response rate in the combined cohort were higher than those in our historical cohort, with a complete response rate of 10% and an overall response rate of 66%. At a median follow-up of 2 years, survival was 97%; one patient died from non-hematologic causes during the study. Bone marrow cellularity, CD34+ cell numbers, and frequency of early hematopoietic progenitor cells were significantly increased.

The most common side effects reported inITPpatients include nausea, diarrhea, upper respiratory tract infection, vomiting, Elevated ALT, myalgia, urinary tract infection, oropharyngeal pain, elevated AST, pharyngitis, back pain, influenza, paresthesia and rash.

The most common side effects of hepatitis C in patients with chronic thrombocytopenia include anemia, fever, fatigue, headache, nausea, diarrhea, decreased appetite, influenza-like illness, weakness, insomnia, cough, pruritus, chills, myalgia, alopecia, and peripheral edema. There are generic drugs overseas, and each box costs about 400 to 1,000 yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.