What are the side effects of Acalabrutinib?

AcalabrutinibAcalabrutinib is a prescription drug used to treat patients with mantle cell lymphoma (cella fast-growing cancer that starts in cells of the immune system) who have been treated with at least one other chemotherapy drug. Acalabrutinib is also used alone or with obinutuzumab (Gazyva) to treat chronic lymphocytic leukemia and small lymphocytic lymphoma (SLL).

Acalabrutinib/Common side effects of acalabrutinib includedecreased hemoglobin (46%), thrombocytopenia (44%), headache (39%)< /span>, Neutropenia (36%), Diarrhea (31%), Fatigue (28%), Myalgia (21%), Bruise ( 21% an>, vomiting (13%), neutropenia (15%), thrombocytopenia (12%), decrease in hemoglobin (10%), etc.

Acalabrutinib/Acalabrutinib is a small molecule inhibitor of BTK. Acalabrutinib/Acalabrutiniband its active metaboliteACP-5862are both compatible withBTKThe cysteine residue (Cys481) in the active site forms a covalent bond, thereby inhibiting BTKEnzyme activity. Therefore, Acalabrutinib/Acalabrutinib inhibits BTK-mediated downstream signaling proteinsCD86 and CD69 ultimately inhibits malignant B cell proliferation and survival. If you want to get more high-quality information, you can contact YaoDe. YaoDe will do its best to learn more about high-quality overseas drugs for you.

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