Quickly learn: the range of applicable diseases of serputinib/serpatinib

Selpercatinib/The indications of Selpercatinib widely cover a variety of cancer types related to RET gene mutations.

1. RET fusion-positive patients with locally advanced or metastatic non-small cell lung cancer (NSCLC): For those in the course of the diseaseOutAppearedRET gene fusion and has progressed to locally advanced or metastatic non-small cell lung cancer. Seputinib is an effective treatment option. The drug's use is based on an FDA-approved test that accurately detects RET gene fusions.

2.Patients with RET-mutant medullary thyroid carcinoma (MTC): Seputinib is also indicated for patients 12 years and older with medullary thyroid cancer whose cancer has progressed to an advanced or metastatic stage and who have a RET gene mutation. This drug provides new treatment opportunities for these patients who require systemic therapy, and its use is also based on an FDA-approved test to detect RET gene mutations.

3.Patients with RET fusion-positive advanced or metastatic thyroid cancer (TC): Seputinib is an effective treatment option for patients 12 years and older with thyroid cancer whose cancer has progressed to an advanced or metastatic stage and who have a RET gene fusion. This drug is particularly useful in patients who have not responded to radioactive iodine therapy (if radioactive iodine is a suitable treatment option) and require systemic therapy.

4.OthersPatients with RET fusion-positive locally advanced or metastatic solid tumors: Seputinib is also suitable for adult patients with RET gene fusion-positive locally advanced or metastatic solid tumors. These patients may have progressed on prior systemic therapy or have no other satisfactory treatment options. This drug offers these patients new treatment opportunities to help control the course of their disease.

Up to now, the original drug is sold in China as Seputinib, but it is not included in medical insurance. The price of each box of specifications80mg*56 capsules may be more than 10,000 yuan. There are European and American versions of the original drugs sold overseas, with the price of each box ranging from 20,000 to more than 100,000 yuan (prices may fluctuate due to exchange rates). Seputinib is also available overseasSeputinibGeneric drugs are on the market, and their drug ingredients are basically the same as those of original drugs sold domestically and abroad. For example, the specifications produced by Laos Pharmaceutical FactoryThe price of each box of 40mg*120 tablets is more than 4,000 yuan (the price may fluctuate due to the exchange rate).