How many bottles of pemetinib/pemetinib are needed for a course of treatment?

Pemigatinib/Pemigatinib is used to treat cholangiocarcinoma (CCA) that has spread or cannot be removed with surgery, in patients who have previously tried cancer treatments, and in which the cancer has a certain type of abnormal FGFR2 gene. Pemetinib is also used to treat myeloid/lymphoid tumors (blood cancers) in patients whose cancers have a certain type of abnormal FGFR1 gene that have recovered or have not responded to treatment. Pemetinib is an antineoplastic (cancer) drug. It interferes with the growth of cancer cells, which are eventually destroyed by the body.

Pemetinib is only available with a doctor's prescription. The recommended dose for patients with cholangiocarcinoma is 13.5 mg of pemetinib taken orally daily for 14 days, and then stopped for 7 days, and every 21 days is a treatment cycle; for patients with bone marrow/lymphoma with FGFR1 rearrangement, the recommended dose is 13.5 mg pemetinib taken orally daily for continuous taking. Treatment should be continued until disease progression or intolerable toxicity occurs. If a patient experiences adverse effects during treatment with pemetinib, their doctor will adjust their drug dose, eventually reducing it to a dose of 4.5 mg once daily for 14 days in each 21-day cycle. If this dose is not tolerated, pemetinib will be permanently discontinued.

Pemetinib tablets sold in China are available in two specifications: 4.5mg*14 tablets per box and 9mg*14 tablets. Patients use the drug to treat one A course of treatment requires about about 3 boxes. The combination of two specifications requires about 2 boxes. The price of each box may be 30,000 to 50,000 yuan. It is estimated that the price of a course of treatment is still very expensive for patients. Currently, this drug is not included in the medical insurance, so patients can only purchase the drug at their own expense.