Instructions for use: Instructions and precautions for taking Cabozantinib

Cabozantinib is a targeted therapy drug used to treat many types of cancer, including renal cell carcinoma, thyroid cancer, and hepatocellular carcinoma. Proper usage and precautions are crucial to ensure the efficacy and safety of the drug. The following are the instructions and precautions for taking cabozantinib:

1.Dosage: Cabozantinib is usually supplied in the form of oral capsules. Once a day, each time60mg, best taken on an empty stomach at the same time. Capsules should be swallowed whole with plenty of water. Do not chew, open or grind capsules.

2.Dose: The dose is usually determined based on factors such as the patient's weight, age, tumor type and tumor severity. The doctor will adjust the dosage according to the patient's condition. While taking the medication, the doctor may recommend checking the patient's blood tests and other physiological indicators regularly to determine the optimal dose.

3.Food and drug interactions: Avoid eating foods containing grapefruit or its juice while taking cabozantinib because grapefruit may affect the metabolism of the drug. Avoid taking other medications while taking cabozantinib, especially medications that may cause interactions. Be sure to tell your doctor about all the medications you are taking, including prescription drugs, over-the-counter drugs, and supplements.

4.Adverse reactions: Cabozantinib may cause a series of adverse reactions, including but not limited to hypertension, hand-foot syndrome, diarrhea, fatigue, rash, dry mouth, etc. If any adverse reactions occur, your doctor should be informed promptly. Your doctor may adjust the dose or take other steps to manage adverse effects.

5.特殊人群：对于肝功能不全或肾功能不全的患者，可能需要调整剂量。 The doctor will make an assessment based on the patient's specific situation. Pregnant and nursing women should avoid cabozantinib due to possible adverse effects on the fetus and infant.

6.Discontinuation and restarting: When serious adverse reactions occur or treatment needs to be suspended, the medication should be stopped according to the doctor's instructions. Once symptoms improve, your doctor will instruct you to restart medication, usually at a lower dose.

7.Storage: Cabozantinib capsules should be stored in a cool, dry place away from direct sunlight and high temperature and humidity. Avoid exposing the medicine to extreme temperatures.

In general, cabozantinib is an effective cancer treatment drug, but you need to closely follow your doctor's instructions during use and pay attention to possible adverse reactions. Patients should be regularly monitored and evaluated by a physician to ensure optimal treatment effectiveness and safety.