Is there a generic version of Seleniso?

The original drug Selinexor (Selinexor) is currently marketed and sold in many overseas countries. It is a drug for the treatment of relapsed or refractory multiple myeloma (R/R MM) and relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL). It is understood that generic drugs of Seleniso are currently produced and sold. Its pharmaceutical ingredients are basically the same as those of the original drug. There may be slight differences in production specifications and prices. Common manufacturers of generic drugs include Laos Lucius Pharmaceutical Factory, Daxiong Pharmaceutical Factory, etc.

In the STORM study for patients with refractory multiple myeloma, the combination of seliniso and dexamethasone achieved an overall response rate of 26.2%. This data provides strong support for its approval in the United States. In addition, selinesol also performs well in early treatment regimens and in combination with other drugs. Preclinical studies have revealed its synergistic effect with a variety of anti-myeloma drugs. In the latest phase 3 trial, the combination of selinesol with bortezomib and low-dose dexamethasone at a once-weekly dosing frequency demonstrated longer progression-free survival, higher overall response rate, lower mortality, and significantly reduced peripheral neuropathy.

Currently, the price of generic Seleniso sold overseas is lower than that of the original drug. The specifications include 20mg*32 tablets and 20mg*16 tablets. The price of each box may be RMB 2-5,000 (the price may fluctuate due to the exchange rate). The specifications of Selinesoloriginal drugs sold at home and abroad include20mg*16 tablets, 20mg*12 tablets, and 20mg*8 tablets. The price per box may be RMB 20,000-150,000 (the price may fluctuate due to the exchange rate. For more information on overseas drug prices and related information, please consult the medical consultant.