Detailed Chinese instructions for lenalidomide

1. Ingredients and properties

Each tablet contains lenalidomide (Lenalidomide) 5mg or 10mg or 15mg or 25mg. Lenalidomide is a dimethyldicarbonyl derivative containing unstable tricyclic and tetracyclic nuclei.

2. Indications

Lenalidomide is suitable for use in the following situations:

1.Untreated multiple myeloma (MM).

2.Multiple myeloma that continues despite treatment (MM).

3.5qChromosome deletion syndrome (specifically manifested as low blood cell countMDS).

3. Usage and dosage

1.Patients should take lenalidomide under the guidance of a doctor and follow the medication regimen according to the doctor's instructions.

2.The generally recommended dose of lenalidomide is to be taken orally once a day, and the recommended dosage is 25 mg.

3.Patients should swallow lenalidomide tablets whole with a glass of water after meals.

4. Adverse reactions

Lenalidomide may cause some adverse reactions, including but not limited to the following symptoms:

1.Anemia, low white blood cells, and low platelets can lead to bleeding, infection, and other blood problems.

2.Digestive tract discomfort, including nausea, vomiting, diarrhea, constipation, etc.

3.Skin reactions, such as rash, dryness, itching, etc.

4.Fatigue, weakness, headache, etc.

5.Thromboembolism may cause serious complications, such as myocardial infarction, stroke, etc.

5. Things to note

1.Before use, you should read the drug instructions carefully and follow your doctor's advice.

2.During the use of lenalidomide, blood tests should be performed regularly to monitor changes in blood indicators.

3.Pregnancy and breastfeeding should be avoided during use. For women of childbearing age, reliable contraceptive measures should be used.

4.For patients who may cause skin reactions, exposure to strong light should be avoided to reduce skin discomfort.

6. Contraindications

1.Patients who are allergic to lenalidomide or any ingredient in the drug.

2.Do not use during pregnancy.

7. Drug interactions

Lenalidomide may interact with other medications, including but not limited to the following:

1.Taking it with anticoagulant drugs including warfarin and drugs that affect platelet function may increase the risk of bleeding.

2.Concurrent use with hepatic metabolic enzyme inducers (such as rifampicin, cyclophosphamide, etc.) may reduce the plasma concentration of lenalidomide.

8. Storage conditions

Lenalidomide tablets should be stored in a cool, dry place away from direct sunlight and moisture.

9. Summary

Lenalidomide is an important immunomodulatory drug used to treat a variety of hematological malignancies. During the use of lenalidomide, patients should pay close attention to the occurrence of adverse reactions and undergo regular blood monitoring and physical examinations. Working closely with your doctor and following your doctor's instructions can minimize the occurrence of adverse reactions and improve the effectiveness of treatment.

10. Listing and price situation

Lenalidomide is now available in China and is covered by medical insurance. Patients can purchase it in the domestic market at a price of approximately 4,000 to 5,000 yuan. For specific prices and medical insurance reimbursement details, please consult the local hospital pharmacy. In addition, there are more affordable generic lenalidomide drugs on the foreign market, such as those produced in Laos, Bangladesh, and India, and the price is only a few hundred yuan. It is worth mentioning that the ingredients of these foreign generic drugs are basically the same as those of domestic original drugs.