Instructions for use and dosage of acotinib

1. Drug name

Acalabrutinib capsules

2. Drug ingredients

Acalabrutinib (Acalabrutinib)

3. Indications

Acotinib is indicated for the treatment of the following diseases:

1.Chronic lymphocytic leukemia (CLL);

2.Small cell lymphoma (SLL);

3.Follicular lymphoma (FL);

4.Diffuse largeB cell lymphoma (DLBCL).

4. Specifications and dosage forms

Acotinib capsules, each capsule contains100mgAcotinib.

5. Usage and Dosage

1.Adult dosage: Take orally twice a day, 100 mg each time, continuously.

2.The medication should be taken after meals and swallowed with a glass of water.

6. Medication for special groups

1.Elderly patients: Generally no dose adjustment is required.

2.Patients with hepatic impairment: Patients with mild hepatic impairment (Child-Pugh A grade) do not need to adjust the dose; patients with moderate hepatic impairment (Child-Pugh B grade) may need to adjust the dose; patients with severe hepatic impairment (Child-Pugh C grade) should use it with caution or contraindicated.

3.Patients with impaired renal function: No dose adjustment is required in patients with impaired renal function.

7. Adverse reactions

1.The most common adverse reactions include headache, leukopenia, anemia, neutropenia, lymphopenia, gastrointestinal reactions (such as diarrhea, nausea, vomiting), fatigue, rash, etc.

2.Severe adverse reactions include bleeding, arrhythmia, pneumonia, abnormal liver function, abnormal renal function, infection, etc. Patients need to be closely monitored for adverse reactions and treated according to specific circumstances.

8. Taboo

1.Patients known to be allergic to acotinib or drug ingredients.

2.Pregnant women, lactating women and women who may be pregnant.

9. Things to note

1.During the use of acotinib, the patient's hematological indicators, liver function, renal function and other related indicators should be regularly monitored.

2.Patients should avoid contact with situations that may cause bleeding during treatment, and seek medical treatment in time to deal with bleeding.

3.Acotinib may affect the electrical activity of the heart, and patients should monitor their electrocardiogram regularly during use.

4.Patients who are receiving acotinib should avoid taking other drugs that may affect the electrical activity of the heart at the same time.

5.Pregnant and lactating women should avoid using acotinib. If necessary, it should be used under the guidance of a doctor and use contraceptive measures.

10. Storage

Please store acotinib capsules in a cool, dry place away from direct sunlight. Keep out of reach of children.

The above is the usage and dosage instructions of acotinib. If you have any questions or discomfort, please consult your doctor or pharmacist in time.