How much does it cost to take brigatinib/brigatinib a month?

Brigatinib/Brigatinib (Brigatinib) has been approved since for the treatment of adults with advanced non-small cell lung cancer. It can be used in patients with certain mutated cancer cells that may cause tumors to grow faster. These patients should also have been treated with crizotinib. Some patients with non-small cell lung cancer have an abnormal enzyme called anaplastic lymphoma kinase (ALK) in their tumor tissue. The full name of this cancer is ALK-positive non-small cell lung cancer. The ALK enzyme causes uncontrolled growth of tumor tissue. Brigatinib blocks the ALK enzyme, thereby inhibiting further tumor growth.

Brigatinib is provided in the form of tablets, with dosages of 30 mg, 90 mg and 180 mg. Common drug specifications on the market include 30 mg 14 tablets and 2 boards, 90 mg 7 tablets or 7 tablets 4 boards, and 180mg 7 tablets 4 boards. According to clinical guidelines, patients were treated with 90 mg brigatinib once daily for the first seven days; thereafter it was increased to 180 mg brigatinib once daily. Take each box of 90mg* 7 tablets * 4 plates of brigatinib as an example. If the drug is not discontinued due to some factors, it is roughly calculated that the patient will need 2 boxes for one month.

The price of the original brigatinib drug on the domestic market is very high. Each box may cost around 10,000 yuan, and a patient may need more than 20,000 yuan to use it for one month. However, overseas markets provide relatively low-priced generics of brigatinib, and the active ingredients of these generics are basically the same as those of the original drugs sold at home and abroad. Take a generic drug of 90 mg and 30 tablets produced by a Bangladesh pharmaceutical factory as an example. The price per box is about 2,000 RMB (the price may fluctuate due to exchange rate changes). Patients may use it for a month for less than 10,000 RMB, and the price will be lower.