Price of generic capmatinib, which manufacturer is better?

The original drug Capmatinib (Capmatinib) is currently marketed and sold in many overseas countries. It is a prescription drug used to treat adult patients with metastatic non-small cell lung cancer whose tumors have mutations that cause MET exon 14 skipping. It is understood that generic drugs of capmatinib are currently produced and sold. Generic drugs refer to drugs produced by other pharmaceutical companies after the patent of the original drug expires. They are similar to the original drug in terms of ingredients, quality, safety and efficacy. There may be slight differences in production specifications and prices.

Capmatinib is a potent and selective methionine receptor inhibitor that shows in vitro and in vivo activity in various methionine-activated cancer models. Capmatinib demonstrated significant antitumor activity in patients with advanced non-small cell lung cancer harboring MET exon 14 skipping mutations, particularly in those who had not received prior treatment. The efficacy of MET-amplified advanced non-small cell lung cancer is better in tumors with high gene copy number than in tumors with low gene copy number. In addition, capmatinib crosses the blood-brain barrier. Preliminary clinical data show that capmatinib monotherapy has low toxic effects in patients with non-small cell lung cancer with abnormal methionine regulation. Mild peripheral edema and nausea are the main toxic effects, and the efficacy is promising.

There are many versions of capmatinib generics sold overseas. Common generic drug manufacturers include Laos Lucius Pharmaceuticals, Daxiong Pharmaceuticals, United Pharmaceuticals, Element Pharmaceuticals, etc. The regular specifications may be200mg*56 tablets, or 200mg*60 tablets. The price of each box may be 3-4,000 yuan, and its price may fluctuate due to exchange rate effects. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.