Teriflunomide (Aubagio) usage instructions

In the field of treatment of immune diseases, teriflunomide (trade name: Aubagio) has brought new treatment options to patients with multiple sclerosis and other patients due to its excellent immunosuppressive properties. Next, we will provide an in-depth analysis of the usage and dosage of this drug to help patients understand how to use it more accurately.

1. How to take

The dosage of teriflunomide is very flexible and patients can choose to take it before, after or with a meal. In order to maintain a stable concentration of the drug in the blood, patients are advised to take it at a fixed time every day. Before taking the medicine, make sure your mouth and esophagus are moist so that the medicine can enter your body smoothly. Please sit or stand, take the medicine with an appropriate amount of warm water, and avoid lying down immediately after taking the medicine to reduce the time the medicine stays in the esophagus.

If the patient accidentally misses a dose, it should be replenished as soon as possible. However, if it is close to the next dose, please skip this missed dose to avoid overdose.

2. Dosage

The dosage of teriflunomide is adjusted based on the patient's condition and tolerance. Generally speaking, patients need to take it orally once a day at a dose of 7mg or 14mg. No dose adjustment is required in patients with mild and moderate hepatic impairment, but this drug is contraindicated in patients with severe hepatic impairment. Additionally, no dose adjustment is required regardless of the patient's renal function.

3. Precautions after stopping medication

After stopping teriflunomide, some patients may need to undergo a drug removal procedure to help the body quickly eliminate drug residues. This is because teriflunomide takes a long time to be metabolized in the body. If the drug is not eliminated, it may stay in the body for up to 2 years. It is important to follow your doctor's instructions to ensure proper management after discontinuation of medication.

4. Adverse reaction monitoring

Although teriflunomide is a relatively safe drug, some adverse reactions may occur, such as headache, dizziness, depression, and insomnia. Patients should pay close attention to their condition during medication. Once these symptoms occur, please seek medical treatment promptly and inform the doctor of the medication status.

In short, it is crucial for patients to master the usage and dosage of teriflunomide. Only by using the drug correctly can it maximize its efficacy while reducing the occurrence of adverse reactions. Currently, teriflunomide has been launched in China and has been included in the medical insurance catalog, and patients can purchase and use it based on medical advice. In addition, generic drugs are available overseas, and patients can choose the appropriate version of the drug according to their needs.